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Measuring Musculoskeletal Symptoms in Patients Receiving Aromatase Inhibitors

2014-07-23 21:10:00 | BioPortfolio

Summary

Current guidelines recommend endocrine treatment with aromatase inhibitors (AIs) in post-menopausal women with hormone receptor-positive breast cancer. Musculoskeletal symptoms are commonly reported with AI treatment,however, we do not have consistent methods to measure these symptoms prospectively. This gap in our knowledge inhibits the ability to test and develop treatments for AI-associated musculoskeletal symptoms. This pilot study will evaluate functional tests and standardized instruments for their ability to prospectively assess musculoskeletal symptoms in women being treated with AIs for breast cancer.

Description

Specific Aims: 1) identify a core set of instruments for measuring musculoskeletal symptoms, 2) model the time course and predictors of change in musculoskeletal symptoms, 3) explore the effect of musculoskeletal symptoms on adherence to AIs in women during the first 6 months of AI treatment.

Methods: We will prospectively assess musculoskeletal symptoms due to treatment with aromatase inhibitors. Post-menopausal women beginning AI treatment for hormone responsive breast cancer will be invited to join this study.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Breast Cancer

Location

Park Nicollet Institute
St. Louis Park
Minnesota
United States
55426

Status

Recruiting

Source

Park Nicollet Institute

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:10:00-0400

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