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Study to Determine the Digestive and Physiological Effects of an Extract From Bran in Healthy Men and Women

2014-08-27 03:15:42 | BioPortfolio

Summary

The primary objective of this trial is to determine whether two doses of an extract from bran demonstrate a prebiotic effect on colonic bacteria (by modulating selected fecal microbial populations, particularly bifidobacteria). The secondary objective is to measure the potential beneficial effects of consuming an extract from bran on the following physiological parameters: laxation, fecal pH, fecal moisture and stool consistency, blood glucose and insulin concentrations, plasma lipid profiles and serum free fatty acids, colonic bacterial short chain fatty acid production, ammonia metabolism and protein degradation, and biomarkers of oxidative stress and inflammation.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Healthy

Intervention

wheat bran extract, control wheat bran extract

Location

Provident CRC
Glen Ellyn
Illinois
United States
60137

Status

Completed

Source

Kellogg Company

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:42-0400

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