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Assessment of Stent Strut Coverage and Endothelial Function After Drug-Eluting Stents

2014-08-27 03:15:43 | BioPortfolio

Summary

The purpose of this study is to compare coronary endothelium function in patients with a zotarolimus-eluting versus a sirolimus-eluting or a everolimus-eluting stents with optical coherence tomography, vasoconstriction in response to acetylcholine, and coronary biomarker level.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Coronary Artery Disease

Intervention

zotarolimus-eluting stent (ENDEAVOR®), sirolimus-eluting stents (CYPHER SELECT® PLUS), everolimus-eluting stents (PROMUS®)

Location

Hyogo College of Medicine
Nishinomiya
Japan
6638501

Status

Recruiting

Source

Hyogo College of Medicine

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:43-0400

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Medical and Biotech [MESH] Definitions

Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.

An analytical technique for resolution of a chemical mixture into its component compounds. Compounds are separated on an adsorbent paper (stationary phase) by their varied degree of solubility/mobility in the eluting solvent (mobile phase).

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Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.

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