Determination of the Predictive Factors in the Reversibility or the Aggravation in the Disorders of the Glucose Metabolism in Cystic Fibrosis Patients

2014-08-27 03:15:44 | BioPortfolio


For some years, the investigators observe an increase of the arisen of diabetes in cystic fibrosis patients However, this diabetes may be reversible. The investigators speak about " Cystic fibrosis related diabetes.". The objective of this project, is to know better what facilitates the appearance and the reversibility of the diabetes, such as the genetic mutations, the respiratory state and the lung infections. Theses knowledges should allow to adapt the screening of diabetes, and its treatment, for the patients affected by cystic fibrosis.

Study Design

Control: Uncontrolled, Intervention Model: Single Group Assignment, Masking: Open Label


Diabetes in Cystic Fibrosis Patients


Prospective cohort with an annual follow-up


Service de Médecine Interne - Centre Hospitalier Lyon Sud
Pierre Bénite




Hospices Civils de Lyon

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:15:44-0400

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Medical and Biotech [MESH] Definitions

An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

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Variation in health status arising from different causal factors to which each birth cohort in a population is exposed as environment and society change.

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