Effect of Countermeasures on Nocturnal Driving Performance

2014-07-23 21:10:26 | BioPortfolio


Sleep deprivation induces degradation of night-time driving ability via sleepiness. Because of conflicts between physiological needs and social or professional activities, it is necessary to develop affordable countermeasure to sleepiness. In real-life driving studies, nap and coffee are efficient countermeasures of sleepiness at the wheel. However the effect of caffeine is quick but brief and varies between individuals. There is a need for more knowledge in order to know what to recommend to drivers. Exposure to 460-nm monochromatic light (blue light) decreases subjective sleepiness and improves performances. One objective of this project is to investigate whether blue light exposure during driving would be useful in a real driving situation when sleepiness becomes acute. Owing to the fact that our knowledge of the effects of exercise on driving is very sparse and to the absolutely need to standardize the bouts of exercise that will be applied to the subjects. One objective of the present study will be to investigate in a simulator study the effects of a bout of moderate exercise on participants driving ability when sleepiness becomes acute. Nocturnal neurobehavioral performance varies widely between individuals and only certain subjects seem significantly affected by sleep loss. It is of interest to find biological markers for sleep drive to identify vulnerable drivers to sleep deprivation or to identify responders to sleepiness countermeasures (i.e., coffee and blue light). One objective of this study is to determine individual differences (genetic, hormonal and cognitive) in the impairment of driving skills induced by sleep loss and in the efficiency of countermeasures (blue light and coffee).

Study Design

Allocation: Non-Randomized, Control: Active Control, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science




Real driving situation, Driving simulator


CHU de Bordeaux Groupe Hospitalier Pellegrin




University Hospital, Bordeaux

Results (where available)

View Results


Published on BioPortfolio: 2014-07-23T21:10:26-0400

Clinical Trials [634 Associated Clinical Trials listed on BioPortfolio]

Use of Driving Tests to Evaluate Patient Performance on Oral Opioids

Many patients seen at Pain Centers are advised not to drive if they are on long-term opioid medications. Although such advice is routinely given considering patients' safety, unnecessary r...

Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving

The proposed study will validate and determine sensitivity of our new driving simulator, created to evaluate driving ability in a related study to show similar driving performance between ...

Effectiveness of a Driving Intervention on Safe Community Mobility for Returning Combat Veterans

The main objective of this study is to discern if an Occupational Therapy Driving Intervention (OT-DI) improves fitness to drive abilities of Combat Veterans and also investigate if result...

Dose-response of Cannabis and Driving

Epidemiological studies have established a link between collisions while driving and cannabis use. With the changing legal landscape around cannabis, there is much interest in determining ...

Evaluating Electronic Devices in a Driving Simulator

The purpose of this study is to evaluate a variety of technologies in a driving simulator. Specifically, this research will provide a direct comparison of driver performance measures under...

PubMed Articles [5901 Associated PubMed Articles listed on BioPortfolio]

Cannabis smoking impairs driving performance on simulator and real driving: A randomized, double blind, placebo-controlled, crossover trial.

Driving experiments in real conditions are considered as a "gold standard" to evaluate the effects of drugs on driving performance. Several constraints are difficult to manage in these conditions, so ...

Simulated car driving and its association with cognitive abilities in patients with schizophrenia.

Patients with schizophrenia commonly suffer from impairments in various aspects of cognition. These deficits were shown to have detrimental effects on daily life functioning and might also impair car ...

Validation of a Driving Simulator Study on Driver Behavior at Passive Rail Level Crossings.

The behavioral validation of an advanced driving simulator for its use in evaluating passive level crossing countermeasures was performed for stopping compliance and speed profile.

A qualitative exploration of driving stress and driving discourtesy.

Driving courtesy, and conversely driving discourtesy, recently has been of great interest in the public domain. In addition, there has been increasing recognition of the negative impact of stress upon...

Driving impairment and crash risk in Parkinson disease: A systematic review and meta-analysis.

To provide the best possible evidence base for guiding driving decisions in Parkinson disease (PD), we performed a meta-analysis comparing patients with PD to healthy controls (HCs) on naturalistic, o...

Medical and Biotech [MESH] Definitions

The effect of environmental or physiological factors on the driver and driving ability. Included are driving fatigue, and the effect of drugs, disease, and physical disabilities on driving.

Behavior which detracts from the focus necessary to operate an automobile safely.

Operating a motor vehicle while impaired by alcohol or other drugs including those prescribed by physicians.

Government required written and driving test given to individuals prior to obtaining an operator's license.

Physiologically, the opposition to flow of air caused by the forces of friction. As a part of pulmonary function testing, it is the ratio of driving pressure to the rate of air flow.

More From BioPortfolio on "Effect of Countermeasures on Nocturnal Driving Performance"

Quick Search


Relevant Topics

Sleep Disorders
Sleep disorders disrupt sleep during the night, or cause sleepiness during the day, caused by physiological or psychological factors. The common ones include snoring and sleep apnea, insomnia, parasomnias, sleep paralysis, restless legs syndrome, circa...

Biological Therapy
Biological therapy involves the use of living organisms, substances derived from living organisms, or laboratory-produced versions of such substances to treat disease. Some biological therapies for cancer use vaccines or bacteria to stimulate the body&rs...

Searches Linking to this Trial