The Effect of High Protein Diet Versus a Low Fat Diet on Body Weight After Smoking Cessation

2014-08-27 03:15:54 | BioPortfolio


The purpose of this study is to determine whether subjects following a high protein diet will gain less in weight after smoking cessation compared to subjects following a low fat diet due to the effects of dietary protein on resting metabolic rate and hunger.


Sustained smoking cessation is one of the most effective therapies to avoid premature morbidity and mortality. However, weight gain associated with nicotine withdrawal may attenuate some of the beneficial health effects and is cited as a major obstacle to quit smoking. The mechanism for the weight gain is not elucidated but reduced resting metabolic rate, reduced total energy expenditure, increased caloric intake and changes in fat metabolism may be involved. Elucidating effective strategies to prevent or reduce post-cessation weight gain may improve health outcomes of smoking cessation.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment




The high protein diet group and the low fat diet group


Department of Preventive Cardiology


Active, not recruiting


Ullevaal University Hospital

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:15:54-0400

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Medical and Biotech [MESH] Definitions

A diet that consists mainly of foods with a high content of protein and limited amounts of CARBOHYDRATES.

A diet that includes foods with a high protein content.

A diet that contains limited amounts of CARBOHYDRATES. This is in distinction to a regular DIET.

Regular course of eating and drinking adopted by a person or animal. This does not include DIET THERAPY, a specific diet prescribed in the treatment of a disease.

A course of food intake that is high in FATS and low in CARBOHYDRATES. This diet provides sufficient PROTEINS for growth but insufficient amount of carbohydrates for the energy needs of the body. A ketogenic diet generates 80-90% of caloric requirements from fats and the remainder from proteins.

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