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Fluid Lavage of Open Wounds (FLOW): Pilot Trial

2014-08-27 03:15:54 | BioPortfolio

Summary

The purpose of this trial is to investigate whether irrigation solution (soap vs. saline solution), or irrigation pressure (high vs. low) will decrease the rate of infection among patients with open fracture wounds.

Description

Open fractures are an important source of morbidity and are associated with delayed union, nonunion, and infection. Preventing infection through meticulous irrigation and debridement is an important goal in management, and different lavage fluids and irrigation techniques (e.g. high or low pressure lavage) have been described for this purpose. There are, however, a limited number of randomized trials comparing irrigating solutions or irrigating technique. We compared the use of castile soap versus normal saline, as well as high versus low pressure pulsatile lavage on the rates of reoperations and complications in patients with open fracture wounds.

Study Design

Allocation: Randomized, Control: Uncontrolled, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Infection

Intervention

Type of fluid lavage solution, Type of fluid lavage pressure

Location

University of Missouri Health Care
Columbia
Missouri
United States
B3H 2A7

Status

Completed

Source

McMaster University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:54-0400

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