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Randomized Controlled Trials of the Effects of Decadron on Swallowing, Airway, and Arthrodesis

2014-07-23 21:10:39 | BioPortfolio

Summary

Anterior cervical discectomy and fusion with or without decompression is a well-established surgical treatment for spine patients with the appropriate indications. Anterior approach involves some retraction that affect the midline structures of the anterior neck. Irritation and swelling may result, leading to postoperative dysphagia and the less common but critically important occurrence of postoperative airway compromise. Steroids given intraoperatively may reduce the incidence of these adverse outcomes by reducing the degree of swelling within the anterior neck subsequent to local surgical tissue trauma.

The investigators hypothesize that the use of steroids intraoperatively provides a significant benefit to the patient, in terms of reduced incidence of dysphagia and airway compromise.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Swallowing

Intervention

Decadron, Saline

Location

Albany Medical Center
Albany
New York
United States
12208

Status

Recruiting

Source

Albany Medical College

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:10:39-0400

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Medical and Biotech [MESH] Definitions

A genus of HALOBACTERIACEAE distinguished from other genera in the family by the presence of specific derivatives of TGD-2 polar lipids. Haloarcula are found in neutral saline environments such as salt lakes, marine salterns, and saline soils.

A family of gram-negative, moderately halophilic bacteria in the order Oceanospirillales. Members of the family have been isolated from temperate and Antarctic saline lakes, solar salt facilities, saline soils, and marine environments.

Spasmodic swallowing of air.

A species of PERCIFORMES commonly used in saline aquaculture.

Water from natural sources which contain significant concentrations of dissolved salts such as sodium chloride.

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