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Observatory on Elderly Patients "Les S.AGES"

2014-08-27 03:16:01 | BioPortfolio

Summary

Primary objective shared by the 3 registries : Describe the different pharmacotherapeutic management in patients :

- DB (Diabetes): with type 2 diabetes, treated with oral and / or injectable antidiabetics

- CP (Chronic Pain): with any disease leading to chronic pain (lasting for more than 3 months)

- AF (Atrial Fibrillation): with ongoing AF or AF diagnosed within 12 months before enrollment

Secondary objectives shared by the 3 observatories:

- Describe the occurrence of clinical events, hospitalizations and death, according to the different medical care conditions, and analyze their predicting factors

- Estimate the resources consumption according to the medical and non medical management of these patients,

- Analyze the impact of some factors (patient's cognitive status, autonomy, renal function ...) on the current practice

Secondary objectives specific shared by DB and AF registries :

- Analyze the geriatric pharmaco-genetic aspects

Specific secondary objectives for each observatory :

- DB : Describe HbA1c level, percentage of responders and body weight evolution according to the different medical care conditions

- CP : Evaluate pain consequences on Daily Living Activities and patient autonomy

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Diabetes Mellitus, Type 2

Location

Sanofi-Aventis Administrative Office
Paris
France

Status

Recruiting

Source

Sanofi-Aventis

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:01-0400

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Medical and Biotech [MESH] Definitions

A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

The time period before the development of symptomatic diabetes. For example, certain risk factors can be observed in subjects who subsequently develop INSULIN RESISTANCE as in type 2 diabetes (DIABETES MELLITUS, TYPE 2).

A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

A type of diabetes mellitus that is characterized by severe INSULIN RESISTANCE and LIPODYSTROPHY. The latter may be generalized, partial, acquired, or congenital (LIPODYSTROPHY, CONGENITAL GENERALIZED).

A life-threatening complication of diabetes mellitus, primarily of TYPE 1 DIABETES MELLITUS with severe INSULIN deficiency and extreme HYPERGLYCEMIA. It is characterized by excessive LIPOLYSIS, oxidation of FATTY ACIDS, production of KETONE BODIES, a sweet smell to the breath (KETOSIS;) DEHYDRATION; and depressed consciousness leading to COMA.

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