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Comparison of Two Doses of Intranasal Dexmedetomidine as Premedication in Children

2014-08-27 03:16:01 | BioPortfolio

Summary

Intranasal dexmedetomidine has shown to be an effective sedative when used prior to anaesthetic induction as premedication. 1mcg/kg intranasal dexmedetomidine was used in previous study and it produced satisfactory sedation in more than 50% of the children at the time of anaesthetic induction with no adverse effect. In this study we aim to compare 1mcg/kg with 2mcg/kg intranasal dexmedetomidine in children. We expect more children would attain satisfactory sedation prior to anaesthetic induction when higher dose is used.

Study Design

Allocation: Randomized, Control: Dose Comparison, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Patient Between 1-8 Years Old Undergoing Elective Surgery at Queen Mary Hospital

Intervention

Dexmedetomidine

Location

QUeen Mary Hospital
Hong Kong
--
Hong Kong
--

Status

Recruiting

Source

The University of Hong Kong

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:01-0400

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