Breast Cancer With Over-expression of erbB2-BRAINSTORM

2014-08-27 03:16:03 | BioPortfolio


This retrospective cohort study aims to improve our understanding of the current paradigm for treatment of brain metastases in erbB2+ breast cancer patients in the Asia Pacific region. We aim to identify approximately 300 erbB2+ breast cancer patients with brain metastases diagnosed between 2006-2008 in 6 countries. Medical records will be analyzed to determine the treatment pattern for brain metastases, including anti-erbB2 therapy. Additional objectives are to understand the impact of anti-erbB2 therapy on survival after brain metastases and to investigate the relationship between anti-erbB2 therapy for brain metastases and: 1) the time interval between diagnosis of erb2+ breast cancer and brain metastasis, and 2) the occurrence of brain metastasis as the only and/or first site of disease progression.

Study Design

Observational Model: Cohort, Time Perspective: Retrospective


Breast Cancer


Anti-erbB2 therapy as part of a treatment regimen for either brain metastases or primary breast cancer


GSK Investigational Site


Active, not recruiting



Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:16:03-0400

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