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A Methodology Study to Assess Cough Counts in Subjects With Acute Upper Respiratory Tract Infections

2014-08-27 03:16:09 | BioPortfolio

Summary

The objectives of this study are: a) to assess the feasibility and sensitivity of manually count cough bouts over a 4-hour period; b) to assess the effects of buckwheat honey and guaifenesin 400 mg immediate release tablets compared to placebo on the frequency and severity of acute cough due to upper respiratory tract infection and c) to evaluate the correlation between cough bout frequency and subjective assessments of cough severity. The hypotheses to be tested is that 10 ml of buckwheat honey and 400 mg of immediate release guaifenesin will significantly reduce the frequency and severity of cough compared to placebo over a 4-hour evaluation period.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Infection

Intervention

Placebo, Guaifenesin, Buckwheat Honey

Location

Indianapolis
Indiana
United States
46240

Status

Active, not recruiting

Source

Wyeth

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:09-0400

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Medical and Biotech [MESH] Definitions

A sweet viscous liquid food, produced in the honey sacs of various bees from nectar collected from flowers. The nectar is ripened into honey by inversion of its sucrose sugar into fructose and glucose. It is somewhat acidic and has mild antiseptic properties, being sometimes used in the treatment of burns and lacerations.

The medical use of honey bee products such as BEE VENOM; HONEY; bee pollen; PROPOLIS; and royal jelly.

An expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

The only family of the buckwheat order (Polygonales) of dicotyledonous flowering plants. It has 40 genera of herbs, shrubs, and trees.

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