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Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen

2010-07-15 17:00:00 | BioPortfolio

Summary

The purpose of this study is to determine wether topical rapamycin is more efficient than topical steroids in the treatment of chronic erosive lichen planus.

Study Design

Allocation: Randomized, Control: Placebo Control, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Oral Lichen Planus

Intervention

TOPICAL SIROLIMUS (RAPAMUNE*), TOPICAL BETHAMETHASONE 0.05%

Location

Hospital Avicenne-APHP
Bobigny
France
93009

Status

Recruiting

Source

University Hospital, Tours

Results (where available)

View Results

Links

Published on BioPortfolio: 2010-07-15T17:00:00-0400

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Medical and Biotech [MESH] Definitions

Oral lesions accompanying cutaneous lichen planus or often occurring alone. The buccal mucosa, lips, gingivae, floor of the mouth, and palate are usually affected (in a descending order of frequency). Typically, oral lesions consist of radiating white or gray, velvety, threadlike lines, arranged in a reticular pattern, at the intersection of which there may be minute, white, elevated dots or streaks (Wickham's striae). (Jablonski, Illustrated Dictionary of Dentistry)

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