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Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention

2014-07-23 21:10:52 | BioPortfolio

Summary

To evaluate the additive value of tadalafil given together with Diamox (acetazolamide) in preventing acute mountain sickness in travelers to high altitude areas.

Description

A randomized controlled study comparing:

Tadalafil [20mg x1/day] and acetazolamide [125mg x2 day], versus Acetazolamide [125mg x2 day] alone, in trekkers to altitude > 3,000 m.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Conditions

Pulmonary Edema

Intervention

Tadalafil and acetazolamide, Acetazolamide

Location

Center of Geographic Medicine
Tel Hashomer
Israel

Status

Recruiting

Source

Sheba Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:10:52-0400

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Medical and Biotech [MESH] Definitions

Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening.

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