Influence of Intracranial Lesions on Bispectral Index

2014-08-27 03:16:14 | BioPortfolio


The purpose of this study is to assess whether BIS values at return of consciousness are different in patients with or without brain tumors.

Study Design

Observational Model: Case Control, Time Perspective: Prospective


Supratentorial Brain Tumor


BIS values at return of consciousness in patients + predicted and measured propofol plasma concentrations, BIS values at return of consciousness in patients + predicted and measured propofol plasma concentrations


University Medical Center Groningen




University Medical Centre Groningen

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:16:14-0400

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Medical and Biotech [MESH] Definitions

A principle of estimation in which the estimates of a set of parameters in a statistical model are those quantities minimizing the sum of squared differences between the observed values of a dependent variable and the values predicted by the model.

Rare and often fatal drug complication which affects patients undergoing long-term treatment with high doses of PROPOFOL. It is characterized by METABOLIC ACIDOSIS; HYPERLIPIDEMIA; RHABDOMYOLYSIS; cardiovascular CIRCULATORY COLLAPSE; CARDIAC FAILURE; and KIDNEY FAILURE.

An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.

The amount of PLASMA flowing to the parts of the KIDNEY that function in the production of urine. It is the amount of plasma perfusing the KIDNEY TUBULES per unit time, generally measured by P-AMINOHIPPURATE clearance. It should be differentiated from RENAL PLASMA FLOW which is approximately 10% greater than the effective renal plasma flow.

Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.

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