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Study to Assess the Efficacy, Safety, and Tolerability of ADL5747 in Patients With Postherpetic Neuralgia

2014-08-27 03:16:19 | BioPortfolio

Summary

The primary purpose of this study is to evaluate the analgesic efficacy of ADL5747 in patients with postherpetic neuralgia (PHN). The secondary objective of this study is to evaluate the safety, tolerability, and pharmacokinetics of ADL5747.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Postherpetic Neuralgia

Intervention

ADL5747, Placebo, Pregabalin

Location

Laszlo J. Mate, MD
West Palm Beach
Florida
United States
33407-2450

Status

Recruiting

Source

Adolor Corporation

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:19-0400

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Medical and Biotech [MESH] Definitions

An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.

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