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Safety of IFNa Kinoid in Systemic Lupus Erythematosus

2014-08-27 03:16:20 | BioPortfolio

Summary

Interferon alpha (IFNa) is involved in the pathogenesis of systemic lupus erythematosus (SLE)and IFNa levels are associated with the severity of the disease. Blocking IFNa could be an attractive therapeutic strategy. Active immunization with IFNa kinoid (IFN-K) induces a polyclonal antibody response.

This study will evaluate the safety of IFN-K in patients with mild to moderate SLE. It will also measure the induction of anti-IFNa antibodies and evaluate the clinical impact on SLE disease.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Conditions

Systemic Lupus Erythematosus

Intervention

IFN-K

Location

Cliniques Universitaires St Luc
Brussels
Belgium
59037

Status

Not yet recruiting

Source

Neovacs

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:20-0400

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