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Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1

2014-07-23 21:10:57 | BioPortfolio

Summary

A physical training program will improve quality of life, participation in physical activity, motor coordination, muscle strength, and bone and muscle strength in children with neurofibromatosis type 1.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Conditions

Neurofibromatosis Type 1

Intervention

Plyometric training program, Control Group

Location

Shriners Hospitals for Children, Salt Lake City
Salt Lake City
Utah
United States
84103

Status

Not yet recruiting

Source

Shriners Hospitals for Children

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:10:57-0400

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Resiliency Training for Patients With NF2 Via Videoconferencing With Skype

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Neurobiology and Treatment of Reading Disability in NF-1

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PubMed Articles [25991 Associated PubMed Articles listed on BioPortfolio]

Effect of A 16 Week Combined Strength and Plyometric Training Program Followed by A Detraining Period on Athletic Performance in Pubertal Volleyball Players.

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Effect of 8 weeks of concurrent plyometric and running training on spatiotemporal and physiological variables of novice runners.

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Medical and Biotech [MESH] Definitions

A group of disorders characterized by an autosomal dominant pattern of inheritance with high rates of spontaneous mutation and multiple neurofibromas or neurilemmomas. NEUROFIBROMATOSIS 1 (generalized neurofibromatosis) accounts for approximately 95% of cases, although multiple additional subtypes (e.g., NEUROFIBROMATOSIS 2, neurofibromatosis 3, etc.) have been described. (From Neurochirurgie 1998 Nov;44(4):267-72)

A type of strength-building exercise program that requires the body muscle to exert a force against some form of resistance, such as weight, stretch bands, water, or immovable objects. Resistance exercise is a combination of static and dynamic contractions involving shortening and lengthening of skeletal muscles.

A highly customized interactive medium or program that allows individuals to learn and practice real world activities in an accurate, realistic, safe and secure environment.

An autosomal dominant disorder with an acronym of its seven features (LENTIGO; ELECTROCARDIOGRAM abnormalities; ocular HYPERTELORISM; PULMONARY STENOSIS; abnormal genitalia; retardation of growth; and DEAFNESS or SENSORINEURAL HEARING LOSS). This syndrome is caused by mutations of PTPN11 gene encoding the non-receptor PROTEIN TYROSINE PHOSPHATASE, type 11, and is an allelic to NOONAN SYNDROME. Features of LEOPARD syndrome overlap with those of NEUROFIBROMATOSIS 1 which is caused by mutations in the NEUROFIBROMATOSIS 1 GENES.

Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2.

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