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Neurally Adjusted Ventilatory Assist (NAVA) in Pediatric Patients

2014-07-23 21:10:59 | BioPortfolio

Summary

The purpose of this study is to find out if NAVA-technology is better in detecting patients own inspiratory efforts during mechanical ventilation than currently used flow-triggering in PRVC (pressure regulated volume controlled) ventilation, and if NAVA gives real benefits for patients or not.

The investigators study hypothesis is that NAVA-technology can detect spontaneous inspiration more accurately than currently used methods, and thus will lead to more smooth adaptation to mechanical ventilation in pediatric patients. The investigators expect this to decrease the time of ventilatory support needed.

Description

Asynchrony means that the timing of support given by ventilator is different from patients own breathing pattern. Asynchrony during ventilatory care may increase the risk for complications, make the weaning more difficult and may affect the survival rates.

In our study we randomly treat pediatric patients needing ventilatory support with neurally adjusted ventilatory assist and pressure controlled or PRVC-ventilation. We are willing to find out if there are any special benefits for patients with each treatment mode.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Ventilation

Intervention

Neurally adjusted ventilatory assist, i-Servo, Maquet Nordic (Solna, Sweden), Control (PC- or PRVC- ventilation), i-Servo, Maquet Nordic (Solna, Sweden)

Location

University Hospital of Oulu
Oulu
Finland

Status

Recruiting

Source

University of Oulu

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:10:59-0400

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Neurally Adjusted Ventilatory Assist (NAVA) in Ventilatory Care of Premature Infants

The purpose of this study is to find out, whetehr it is possible to improve the ventilatory care of premature infants by using Neurally adjusted ventilatory assist (NAVA). Investigators s...

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Neurally adjusted ventilatory assist (NAVA) is a new concept of mechanical ventilation. NAVA delivers assist to spontaneous breathing based on the detection of the electrical activity of t...

PubMed Articles [2189 Associated PubMed Articles listed on BioPortfolio]

Standardized Unloading of Respiratory Muscles during Neurally Adjusted Ventilatory Assist: A Randomized Crossover Pilot Study.

WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Currently, there is no standardized method to set the support level in neurally adjusted ventilatory assist (NAVA). The primary aim was to explore ...

Neurally adjusted ventilatory assist in extremely low birth weight infants.

Neurally adjusted ventilatory assist (NAVA) is expected to improve respiratory outcomes in preterm infants; however, it has not yet been evaluated. We investigated whether NAVA could improve respirato...

Patient-ventilator asynchrony.

Patient-v entilator asynchrony (PVA) is a mismatch between the patient, regarding time, flow, volume, or pressure demands of the patient respiratory system, and the ventilator, which supplies such dem...

Ventilation Parameters under Adaptive Servo Ventilation: A Comparison on Behalf of CSA-Pattern, BNP/NT-pro-BNP, and Ejection Fraction.

The SERVE-HF study has raised questions concerning the higher mortality under adaptive servoventilation. The ventilatory mode was discussed as a possible aggravating factor.

Principles for managing OUD related to chronic pain in the Nordic countries based on a structured assessment of current practice.

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Medical and Biotech [MESH] Definitions

NORWAY; SWEDEN; DENMARK; ICELAND; and FINLAND.

The state wherein the person is well adjusted.

Mechanical ventilation delivered to match the patient's efforts in breathing as detected by the interactive ventilation device.

Drug-induced depression of consciousness during which patients cannot be easily aroused but respond purposely following repeated painful stimulation. The ability to independently maintain ventilatory function may be impaired. (From: American Society of Anesthesiologists Practice Guidelines)

An occupational discipline founded by D.D. Palmer in the 1890's based on the relationship of the spine to health and disease. The spine is analyzed by X-rays and palpation, and vertebrae are adjusted manually to relieve pressures on the spinal cord. OSTEOPATHIC MEDICINE was originally similar but has become more like FAMILY PRACTICE.

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