Advertisement

Topics

To Assess the Safety of Avanafil in Healthy and Hepatically Impaired Male Subjects.

2014-08-27 03:16:27 | BioPortfolio

Summary

The objective of this study is to assess the single dose pharmacokinetics of avanafil in subjects with hepatic impairment and in healthy control subjects.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Erectile Dysfunction

Intervention

avanafil

Status

Active, not recruiting

Source

VIVUS, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:27-0400

Clinical Trials [587 Associated Clinical Trials listed on BioPortfolio]

Research Evaluating an Investigational Medication for Erectile Dysfunction - Post-Prostatectomy

The objectives of this study are to evaluate the safety and efficacy of two doses of avanafil in the treatment of adult males for erectile dysfunction following bilateral nerve-sparing rad...

Long-Term Safety and Efficacy Study of Avanafil in Men With Erectile Dysfunction

This open-label study is being conducted to evaluate the long-term safety, tolerability, and efficacy of avanafil in men with mild to severe erectile dysfunction. Approximately 400 subject...

Research Evaluating an Investigational Medication for Erectile Dysfunction - General ED

This study is being conducted to compare the safety and efficacy of 3 doses of avanafil to placebo in men with mild to severe erectile dysfunction.

Avanafil Versus Sildenafil in Spinal Cord Injury Erectile Dysfunction

The main goal of this study is to compare the use of Avanafil versus Sildenafil in spinal cord injury erectile dysfunction. The study has the characteristics of a non- inferiority, randomi...

A Thorough EKG Safety Study of TA-1790 (Avanafil)

This study is to assess whether treatment with a therapeutic (100 mg) or supratherapeutic (800 mg) dose of avanafil has the potential to cause QT/QTc prolongation in healthy volunteers.

PubMed Articles [3077 Associated PubMed Articles listed on BioPortfolio]

Predictors of Erectile Function Normalization in Men With Erectile Dysfunction Treated With Placebo.

Clinical study and practice data have shown sildenafil improves sexual function in men with erectile dysfunction (ED). However, some men treated with placebo in double-blind, placebo-controlled silde...

Penile erectile strength measurement band for differentiation and classification of erectile dysfunction.

To study the clinical application value of the penile erectile strength measurement (PESM) band in the differentiation of psychogenic from organic erectile dysfunction (ED).

Penile rehabilitation for postprostatectomy erectile dysfunction.

Despite efforts to preserve the neurovascular bundles with nerve-sparing surgery, erectile dysfunction remains common following radical prostatectomy. Postoperative penile rehabilitation seeks to rest...

Clinical Profile of Young Patients with Erectile Dysfunction: Preliminary Findings of a Real-life Cross-sectional Study.

Erectile dysfunction (ED) is an increasingly common complaint among men aged

Erectile dysfunction and psychological status in infertile males.

To investigate the relationship of erectile dysfunction (ED) with psychological factors in male patients with infertility.

Medical and Biotech [MESH] Definitions

The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction.

Inability to achieve and maintain an erection (ERECTILE DYSFUNCTION) due to defects in the arterial blood flow to the PENIS, defect in venous occlusive function allowing blood drainage (leakage) from the erectile tissue (corpus cavernosum penis), or both.

Surgical insertion of cylindric hydraulic devices for the treatment of organic ERECTILE DYSFUNCTION.

Drugs used in the treatment of urogenital conditions and diseases such as URINARY INCONTINENCE; PROSTATIC HYPERPLASIA; and ERECTILE DYSFUNCTION.

A carboline derivative and PHOSPHODIESTERASE 5 INHIBITOR that is used primarily to treat ERECTILE DYSFUNCTION; BENIGN PROSTATIC HYPERPLASIA and PRIMARY PULMONARY HYPERTENSION.

More From BioPortfolio on "To Assess the Safety of Avanafil in Healthy and Hepatically Impaired Male Subjects."

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topics

Hepatology
Hepatology is the study of liver, gallbladder, biliary tree, and pancreas, and diseases associated with them. This includes viral hepatitis, alcohol damage, cirrhosis and cancer. As modern lifestyles change, with alcoholism and cancer becoming more promi...

Nutrition
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...


Searches Linking to this Trial