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This is a Phase 1 study to understand the manner in which the body responds to, as well as how the drug is handled by the body, with once vs twice daily dosing of PF-04971729 in patients with type 2 diabetes.
Phase 1 PK-PD study to understand the body's response to twice daily versus once daily dosing of PF-04971729. This study also plans to study how the body handles PF-04971729.
Allocation: Randomized, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator)
Diabetes Mellitus, Type 2
2 mg single dose, 2 mg split into twice daily, 4 mg single dose, 4 mg split into twice daily
Pfizer Investigational Site
Published on BioPortfolio: 2014-08-27T03:16:27-0400
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The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
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A treatment schedule in which the total dose of radiation is divided into large doses.
The highest dose of a biologically active agent given during a chronic study that will not reduce longevity from effects other than carcinogenicity. (from Lewis Dictionary of Toxicology, 1st ed)
Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...