Expression and Localization of FP Prostaglandin Receptor in Human Ocular Tissues

2014-08-27 03:16:27 | BioPortfolio


to approve the expression of PGF2α receptors in hair follicle in ocular skin tissue, explaining the hypertrichotic effect of PG analogues as intraocular pressure lowering treatment.


50 hair follicle dissection - human lower lid skin and lashes will be derived from lateral tarsal strip (LTS) dissected routinely in ectropion repair surgery, the skin strip is dissected routinely in this surgery , without any relation to our study. The study will be planned according to Helsinki declaration for Paraffin embedded LTS tissue sections (4 µ) will be processed and examined in immunohistochemistry lab. FP receptor proteins expression, using subtype-specific polyclonal antibodies, will be detected by the light microscopic level, according to manufacturer instruction.

Study Design

Observational Model: Case-Only, Time Perspective: Prospective


Malposition of the Lower Lid


Not yet recruiting


Meir Medical Center

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:16:27-0400

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