Placebo Effect of Paracetamol in Healthy Volunteers

2014-08-27 03:16:28 | BioPortfolio


Paracetamol is one of the most commonly used drugs in the world, indicated for the symptomatic treatment of fever and pain of mild to moderate. More precisely, it is a drug used to relieve pain and reduce fever. The objective of this study is to analyze whether a placebo effect occurs when you take paracetamol for pain, ie if the analgesic effect of paracetamol is partly due to the simple fact of taking a drug.

Moreover, during the study you propose to do a saliva sample, optional, for biological research, pharmacogenetics, to assess how paracetamol is processed and eliminated in your body..


Clinical trial conducted in healthy volunteers, prospective, single center, randomized, open / hidden.

Study Design

Allocation: Randomized, Control: Uncontrolled, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment


Healthy Volunteers




CHU Clermont-Ferrand


Not yet recruiting


University Hospital, Clermont-Ferrand

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:16:28-0400

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A deep blue dye (with the formula OC6H4NC6H4OH) used to detect AMMONIA in a common test called the Berthelot's reaction and to detect PARACETAMOL by spectrophotometry.

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