The Association Between Dopamine Agonists and Cardiac Valvulopathy, Fibrosis and Other Cardiopulmonary Events
Summary
To assess the association between cabergoline and other dopamine agonists (DAs), and symptomatic, diagnosed serious cardiopulmonary disorders, including:
1. Cardiac valve regurgitation
2. Diffuse Pleural/pulmonary thickening and pericardial and retroperitoneal fibrosis
4. Total, cardiac and respiratory mortality
Study Design
Observational Model: Cohort, Time Perspective: Retrospective
Conditions
Parkinson's Disease
Intervention
Retrospective study-, Retrospective study-, Retrospective study-, Retrospective study-
Status
Completed
Source
Pfizer
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT01052948
- Information obtained from ClinicalTrials.gov on July 15, 2010
Published on BioPortfolio: 2014-07-23T21:11:02-0400
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Medical and Biotech [MESH] Definitions
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Retrospective Moral Judgment
The application of current standards of morality to past actions, institutions, or persons.
Observational Study
A work that reports on the results of a clinical study in which participants may receive diagnostic, therapeutic, or other types of interventions, but the investigator does not assign participants to specific interventions (as in an interventional study).
Multicenter Study
Work consisting of a controlled study executed by several cooperating institutions.
Historically Controlled Study
A study that compares a group of participants receiving an intervention with a similar group from the past who did not.
