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Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites

2014-08-27 03:16:32 | BioPortfolio

Summary

The purpose of the trial is to asses the efficacy and safety of sublingual annual immunotherapy in children with bronchial asthma and/or allergic rhinitis allergic to house dust mites.

Description

Allergen immunotherapy is currently the only one method of cause treatment of the IgE-dependent allergic diseases. Sublingual immunotherapy (SLIT) is the method which allows to give allergens via alternative oral route in patients home. Due to possibility of avoiding injection this therapy offers better relationship with pediatric patient. However efficacy and safety of sublingual immunotherapy are still important issues, especially in asthmatic children. The purpose of the trial is to asses the efficacy and safety of sublingual annual immunotherapy in children with bronchial asthma and/or allergic rhinitis allergic to house dust mites.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Conditions

Bronchial Asthma

Intervention

sublingual house dust mites allergen extract, placebo in sublingual applicator

Location

Department of Pediatrics and Allergy
Lodz
Poland
93-513

Status

Not yet recruiting

Source

Medical Universtity of Lodz

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:32-0400

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PubMed Articles [3336 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

A form of retention cyst of the floor of the mouth, usually due to obstruction of the ducts of the submaxillary or sublingual glands, presenting a slowly enlarging painless deep burrowing mucocele of one side of the mouth. It is also called sublingual cyst and sublingual ptyalocele.

Neoplasms of the sublingual glands.

Family of house dust mites, in the superfamily Analgoidea, order Astigmata. They include the genera Dermatophagoides and Euroglyphus.

Species of European house dust mite, in the family PYROGLYPHIDAE. It is the most commonly found house dust mite.

A method of treating an ALLERGY by administering ALLERGENS, in liquid formulation or tablets, to the ORAL MUCOSA under the tongue.

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