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PK and PD of Drugs for Nontuberculous Mycobacterial Diseases in Dutch Patients

2014-07-24 14:10:17 | BioPortfolio

Summary

A prospective observational study in which pharmacokinetic and pharmacodynamic parameters are evaluated in a cohort of patients with NTM diseases.

Description

NTM are widely distributed in the environment and can especially be found in soil and water sources. These bacteria a very similar to tuberculosis bacteria. We are not that long aware that these bacteria can cause illness. Especially in patients with a chronic lung disease are sensitive to these bacteria and are susceptible to develop an infection. A lot of ambiguity consists about the best treatment of these infections. Up till now mainly the normal treatment for tuberculosis is used, however, the time period during which these medicines should be used and what dose should be used is mainly unknown.

To investigate whether the dose used at this moment is right a pharmacokinetic curve will be taken at steady-state.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Nontuberculous Mycobacterial Diseases

Location

Radboud University Medical Centre Nijmegen
Nijmegen
Gelderland
Netherlands

Status

Recruiting

Source

Radboud University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:10:17-0400

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