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Magnetic Resonance Imaging Study of Lisdexamfetamine for Bipolar Depression

2014-08-27 03:16:34 | BioPortfolio

Summary

The study will use neuroimaging techniques to determine whether brain activity and neurotransmitter levels are altered when lisdexamfetamine is given to subjects with bipolar disorder who are in a depressive phase. Lisdexamfetamine is a stimulant that is currently approved for attention deficit attention disorder (ADHD). The primary hypothesis is that subjects taking lisdexamfetamine will show a greater antidepressant effect than subjects taking placebo. It is also expected that subjects taking the medication will show greater changes in brain activity in regions related to mood as well as improvements in attention on cognitive tests.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Bipolar Depression

Intervention

Lisdexamfetamine, Placebo

Location

Caritas St. Elizabeth's Medical Center
Boston
Massachusetts
United States
02135

Status

Recruiting

Source

Caritas St. Elizabeth's Medical Center of Boston

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:34-0400

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