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AeriSeal System for Lung Volume Reduction

2014-07-24 14:10:17 | BioPortfolio

Summary

The purpose of this study is to evaluate the safety and efficacy of AeriSeal treatment in patients with advanced emphysema.

Description

The purpose of this study is to evaluate the safety and efficacy of AeriSeal treatment in patients with advanced homogeneous and heterogeneous emphysema.

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Emphysema

Intervention

AeriSeal System

Location

Otto Wagner Spital Wien Interne Lungenabteilung
Wien
Austria

Status

Active, not recruiting

Source

Aeris Therapeutics

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:10:17-0400

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Clinical Investigation of a Modified Staged Treatment Algorithm Using the AeriSeal System

A multicenter, prospective, single-arm clinical investigation to evaluate the short term and long term safety of a modified staged treatment algorithm using the AeriSeal System.

Netherlands 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation

The purpose of this study is to determine the effective dose of the Aeris BLVR System in patients with advanced emphysema.

Israeli 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation

The purpose of this study is to evaluate the safety and efficacy of the Aeris BLVR System in patients with advanced emphysema.

Clinical Trial to Evaluate the Safety and Effectiveness of the IBV® Valve System for the Treatment of Severe Emphysema

This trial is for men and women between the ages of 40 and 74 who have a confirmed diagnosis of emphysema. The objective of the trial is to determine the safety and effectiveness of the IB...

Biomarkers and Genetic Factors Related to Emphysema

Emphysema, a common type of chronic obstructive pulmonary disease (COPD), is a long-term lung disease that is usually caused by cigarette smoking. This study will examine both current smok...

PubMed Articles [8049 Associated PubMed Articles listed on BioPortfolio]

Free Desmosine is a Sensitive Marker of Smoke-Induced Emphysema.

While the elastin-specific crosslinks, desmosine and isodesmosine (DID), are increased in blood, urine, and sputum of patients with clinically documented pulmonary emphysema, the usefulness of DID in ...

Management of extensive surgical emphysema with subcutaneous drain: A case report.

Subcutaneous emphysema (SE) is a frequent and often self-limiting complication of tube thoracostomy or other cardiothoracic procedures. On rare occasions, severe and extensive surgical emphysema marke...

Intermittent Exposure to Cigarette Smoke Increases Lung Tumors and the Severity of Emphysema More Than Continuous Exposure.

Lung cancer and chronic obstructive pulmonary disease (COPD) are leading causes of morbidity and mortality worldwide, and cigarette smoking is a main risk factor for both. The presence of emphysema, a...

The effect of emphysema on readmission and survival among smokers with heart failure.

Heart Failure (HF) and chronic obstructive pulmonary disease (COPD) are morbid diseases that often coexist. In patients with coexisting disease, COPD is an independent risk factor for readmission and ...

Aerophagia and subcutaneous emphysema in a patient with Rett syndrome.

A patient with Rett syndrome presented to our Emergency Department with extensive subcutaneous emphysema in the cervical region, chest wall, upper extremities, and back. Diagnostic evaluation revealed...

Medical and Biotech [MESH] Definitions

Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions.

A pathological accumulation of air in tissues or organs.

Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma.

Presence of air or gas in the subcutaneous tissues of the body.

Presence of air in the mediastinal tissues due to leakage of air from the tracheobronchial tree, usually as a result of trauma.

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