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Retrospective Case Study to Validate Existing Chemoresponse Marker Test in Ovarian, Peritoneal or Fallopian Cancer Cases

2014-08-27 03:16:40 | BioPortfolio

Summary

The purpose of this study is to improve upon and validate the prognostic and/or predictive accuracy of a drug response marker by the development of improved alternative algorithms based on the actual clinical outcome of retrospective cases.

Description

This is a multicenter, retrospective chart review study of de-identified drug response marker results and a limited data set of clinical outcome data. Data from approximately 512 cases will be collected from approximately 30 sites and correlated to the secondary endpoints identified in order to produce a training set that will incorporate additional improvements to the existing ChemoFx scoring system. The outcome of progression free survival will be defined as the period of time between the first dose of chemotherapy following the report of the marker result until clinical progression or death. Objective response will be measured from the first dose of chemotherapy following the report of the marker result until progression or change in therapy.

Study Design

Observational Model: Case-Only, Time Perspective: Retrospective

Conditions

Ovarian Cancer

Intervention

ChemoFx

Location

Precision Therapeutics, Inc.
Pittsburgh
Pennsylvania
United States
15203

Status

Enrolling by invitation

Source

Precision Therapeutics

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:40-0400

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