Multidisciplinary Approach to Reduce Injury and Substance Abuse

2014-07-24 14:10:20 | BioPortfolio


The primary purpose of the project entitled: Multidisciplinary Approach to Reduce Injury and Substance Abuse, which is funded by the National Institute on Drug Abuse (5R01DA026088-02), is to compare the effectiveness of brief intervention, brief intervention plus a booster, and brief advice for adult patients who abuse drugs and present to a trauma department for treatment of an injury.


Multidisciplinary Approach to Reduce Injury and Substance Abuse is a randomized clinical trial evaluating the effectiveness of brief advice (BA), brief motivational intervention with feedback (BMI), and brief motivational intervention with feedback and booster (BMI+B) in injured patients with drug problems.

The setting is UMC Brackenridge Hospital Trauma Department, which serves a large and diverse patient population. Injured patients are screened for eligibility in the project based on a positive tox screen or self reported drug use in the past 90 days. The primary outcome of interest will be patients' subsequent drug use. Other outcomes of interest include: HIV-related risk behaviors, improved health outcomes (including injury reduction), increased employment, decreased engagement in illegal behavior, increased substance abuse treatment utilization, and enhanced quality of life at three, six, and twelve month follow-ups.

This study will also examine the potential moderating and mediating effects of patient readiness to change, use of experiential and behavioral processes of change and decisional balance considerations. In addition, this project will examine implementation factors at the organizational level and the cost effectiveness of BA, BMI, and BMI+B.

Study participants and their related identifying information will be collected during the time they are admitted to the UMC Brackenridge Hospital Trauma Department. Study participants must be 18 years or older, speak English or Spanish, have been admitted to the UMC Brackenridge Hospital Trauma Department, and test positive for illegal drugs or admit to illegal drug use when verbally screened. Additional information will be collected from participants in appointments at UMC Brackenridge at three, six, and 12 month follow-up periods.

Study Design

Allocation: Randomized, Control: Dose Comparison, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Prevention


Drug Abuse Among Patients Admitted to a Trauma Department.


Brief advice, Brief Intervention plus Booster Session (BMI+B), Brief Intervention


University Medical Center Brackenridge
United States


Not yet recruiting


National Institute on Drug Abuse (NIDA)

Results (where available)

View Results


Published on BioPortfolio: 2014-07-24T14:10:20-0400

Clinical Trials [817 Associated Clinical Trials listed on BioPortfolio]

Virtual Reality Based Cue-exposure Treatment for Bulimia Nervosa

Introduction: The purpose of this research is to develop a new component for cognitive-behavioral treatment (CBT), empirically validated, for binge eating behavior in patients with bulimia...

Multimodal Sleep Intervention Using Wearable Technology

This research study is examining three different components of a mobile sleep intervention: web-based sleep hygiene advice, sleep and alcohol diary self-monitoring, and personalized sleep ...

Resources to Enhance the Adjustment of Children (REACH)

This continuation study evaluates the long-term outcomes of multimodal, modular interventions with early-onset behavior disordered children and innovative methods to promote the maintenanc...

Sheffield Physical Activity Booster Trial

Adults that increase their physical activity can improve their health, and reduce future risks to health, but long−term changes are difficult to sustain. This study assesses whether it i...

Effectiveness of Written Dietary Advice on Lipoproteins - a Pragmatic Randomized Controlled Trial

This study investigates the effect of detailed, written dietary advice for improving blood lipids, in a primary care setting. n=222 participants will be randomized to Active Intervention o...

PubMed Articles [4411 Associated PubMed Articles listed on BioPortfolio]

An FSH booster surge for resurgence of the preovulatory follicle in heifers.

Emergence of wave 1 during an interovulatory interval (IOI) in heifers is stimulated by FSH surge 1. A minor FSH surge with absence of a dominant follicle in the associated follicular wave occurs imme...

Development of a coping intervention to improve traumatic stress and HIV care engagement among South African women with sexual trauma histories.

This paper describes the development and preliminary trial run of ImpACT (Improving AIDS Care after Trauma), a brief coping intervention to address traumatic stress and HIV care engagement among South...

Do People Inherently Dislike Uncertain Advice?

Research suggests that people prefer confident to uncertain advisors. But do people dislike uncertain advice itself? In 11 studies ( N = 4,806), participants forecasted an uncertain event after receiv...

The impact of booster seat use on child injury and mortality: Systematic review and meta-analysis of observational studies of booster seat effectiveness.

To determine through systematic review and meta-analysis of observational studies if booster seats, compared to seatbelts alone, reduce injury and mortality from motor vehicle collisions among child p...

A Single Session Intervention (The Mini AFTERc) For Fear of Cancer Recurrence: A Feasibility Study.

Medical and Biotech [MESH] Definitions

A study in which observations are made before and after an intervention, both in a group that receives the intervention and in a control group that does not.

A study that uses observations at multiple time points before and after an intervention (the "interruption"), in an attempt to detect whether the intervention has had an effect significantly greater than any underlying trend over time.

Vaccines that are produced by using only the antigenic part of the disease causing organism. They often require a "booster" every few years to maintain their effectiveness.

A form of group psychotherapy. It involves treatment of more than one member of the family simultaneously in the same session.

Individuals referred to for expert or professional advice or services.

More From BioPortfolio on "Multidisciplinary Approach to Reduce Injury and Substance Abuse"

Quick Search


Relevant Topics

Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...

Drug Discovery
Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...

Searches Linking to this Trial