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Targeting Microvascular Dysfunction in Young Hypertensive Patients

2014-08-27 03:16:45 | BioPortfolio

Summary

Cholesterol and blood pressure lowering tablets have been shown to be of benefit in patients with established high blood pressure. High blood pressure is a very common medical condition that can lead to vascular complications i.e. problems with the blood vessels in the body. One way of detecting early changes in these blood vessels as a result of high blood pressure is to measure their compliance/flexibility with a noninvasive technique known as ultrasound and with a simple blood test. The investigators are trying to establish whether these early changes in blood vessels can be significantly improved by the use of both a cholesterol and blood pressure lowering tablet at an earlier stage than is currently advised. The investigators hope that the early combination of these tablets will prove more effective than the use of a blood pressure lowering tablet by itself and therefore possibly reduce the risk of long term complications developing.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Pharmacokinetics/Dynamics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Preve

Conditions

Hypertension

Intervention

Simvastatin, Placebo

Location

Belfast health and social care trust
Belfast
United Kingdom
BT9 7BL

Status

Recruiting

Source

Queen's University, Belfast

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:45-0400

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