Group Rehabilitation for Renal Patients

2014-08-27 03:16:45 | BioPortfolio


The purpose of the study is:

1. to determine the long-term effectiveness of a 12 weeks lasting physical exercise training program.

2. to determine the cost effectiveness of the 12 weeks lasting physical exercise training program.


Exercise intolerance and skeletal muscle weakness are common in dialysis and renal transplant patients and severely compromise quality of life. In an earlier study, the short-term effectiveness of an intensive, supervised exercise training program (twice weekly during a period of 12 weeks; combination of endurance and resistance training) has been investigated in a natural groups cohort study. Exercise training seemed to have beneficial effects on exercise capacity, skeletal muscle strength and quality of life of renal transplant and hemodialysis patients.

The long-term effectiveness and cost-effectiveness of exercise training programs for renal transplant and dialysis patients have, however, not yet been established. Therefore, the long-term effectiveness and cost-effectiveness of an intensive, supervised exercise training program will be investigated in a randomized controlled design in renal transplant and dialysis patients.

Results of such a study are important to convince health care insurers that exercise training is (cost)effective and has to be considered as a structural part of the routine treatment of renal transplant and dialysis patients and therefore should be routinely reimbursed.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Renal Insufficiency


rehabilitation / physical training


6085 NM


Not yet recruiting


Maastricht University Medical Center

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:16:45-0400

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Medical and Biotech [MESH] Definitions

Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE. The most severe form is KIDNEY FAILURE. Renal function may deteriorate slowly (RENAL INSUFFICIENCY, CHRONIC) or precipitously (RENAL INSUFFICIENCY, ACUTE).

A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.

Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)

Bis(nitrato-O)dioxouranium. A compound used in photography and the porcelain industry. It causes severe renal insufficiency and renal tubular necrosis in mammals and is an effective lymphocyte mitogen.

A medical specialty concerned with the use of physical agents, mechanical apparatus, and manipulation in rehabilitating physically diseased or injured patients.

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