Advertisement

Topics

Symptom Burden in Chronic Myeloid Leukemia (CML)

2014-07-23 21:11:10 | BioPortfolio

Summary

The objective of this study is to measure and delineate the symptom burden experienced by patients with chronic myeloid leukemia (CML).

The Primary Aim is to develop and validate an M. D. Anderson Symptom Inventory (MDASI) module (the MDASI-CML), compliant with FDA standards for patient-reported outcomes (PROs), to measure the severity of multiple symptoms and the impact of these symptoms on daily functioning in patients with CML.

Description

There are 3 parts to this study. In Part 1, patients will complete interviews and questionnaires about CML symptoms once. In Part 2, the importance of some symptoms to patients with CML will be rated by physicians, nurses, patients, and caregivers. In Part 3, patients will complete questionnaires about CML symptoms over 1 year.

Up to 218 participants will take part in this study. Up to 40 will be enrolled in Part 1 of this study. Up to 160 participants will be enrolled in Part 3 of this study. All will be enrolled at M. D. Anderson.

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Conditions

Leukemia

Intervention

Interview & Questionnaires, Rating Questionnaire, MDASI-CML Questionnaire

Location

UT MD Anderson Cancer Center
Houston
Texas
United States
77030

Status

Recruiting

Source

M.D. Anderson Cancer Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:11:10-0400

Clinical Trials [3554 Associated Clinical Trials listed on BioPortfolio]

Influence of Audiovisual Aids in the Preanesthetic Interview

1000 patients will be asked to fill out a questionnaire about preanesthetic visit right after the interview. On a daily randomization the Groups will be assigned to: Group A = face-to-face...

Impact of Emotional Skills of Young Women and Their Partner on Adjustment to Cancer

The KALICOU 3 study will evaluate the effect of emotional skills of patients and their partners on their individual disease subjective experience during care pathways, from chemotherapy to...

The Efficacy of a VR Enhanced Video Exposure Therapy for Dental Phobia

Evaluation of a one session VR - enhanced Video exposure therapy for dental phobia. Diagnosed dental phobics will be randomly assigned to one of two conditions: (1) Psychoeducation + VR ex...

Quality of Life Study for Adult Patients With Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) accounts for about 20% of adult leukemias. Treatment results in adult ALL have lagged behind the improvements achieved in the pediatric population. A mod...

Gastrointestinal Symptom Questionnaire Validation

Assessment of a new gastrointestinal symptom questionnaire in comparison to 2 well established and validated questionnaires that do not fully fit the requirements of an investigator concer...

PubMed Articles [3778 Associated PubMed Articles listed on BioPortfolio]

Validity and Clinically Meaningful Changes in the Psychosexual Daily Questionnaire and Derogatis Interview for Sexual Function Assessment: Results From the Testosterone Trials.

Limited information is available on the performance characteristics of 2 questionnaires commonly used in clinical research, the Psychosexual Daily Questionnaire (PDQ) and the Derogatis Interview for S...

Psychometric testing of the healthy eating and physical activity self-efficacy questionnaire and the healthy eating and physical activity behavior recall questionnaire for children.

The purpose of this study was to develop and assess the psychometric properties for two related questionnaires: the Healthy Eating and Physical Activity Self-Efficacy Questionnaire for Children (HEPAS...

The PHQ-9 Item 9 based screening for suicide risk: a validation study of the Patient Health Questionnaire (PHQ)-9 Item 9 with the Columbia Suicide Severity Rating Scale (C-SSRS).

Item 9 of the Patient Health Questionnaire (PHQ) evaluates passive thoughts of death or self-injury within the last two weeks, and is often used to screen depressed patients for suicide risk. We aimed...

Using Web-Based Questionnaires to Assess Medication Use During Pregnancy: A Validation Study in 2 Prospectively Enrolled Cohorts.

Medication use is often underreported in paper-based questionnaires or interviews. Web-based questionnaires may improve recall of medication use, but data on their validity are currently lacking. Part...

Morningness-Eveningness questionnaire in bipolar disorder.

The Morningness-Eveningness Questionnaire (MEQ) is among the most commonly used scales to measure chronotype. We aimed to evaluate psychometric properties and clinical correlates of MEQ in bipolar dis...

Medical and Biotech [MESH] Definitions

Self report questionnaire which yields 16 scores on personality traits, such as reserved vs. outgoing, humble vs. assertive, etc.

Self-administered health questionnaire developed to obtain details of the medical history as an adjunct to the medical interview. It consists of 195 questions divided into eighteen sections; the first twelve deal with somatic complaints and the last six with mood and feeling patterns. The Index is used also as a personality inventory or in epidemiologic studies.

Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.

An iterative questionnaire designed to measure consensus among individual responses. In the classic Delphi approach, there is no interaction between responder and interviewer.

True-false questionnaire made up of items believed to indicate anxiety, in which the subject answers verbally the statement that describes him.

More From BioPortfolio on "Symptom Burden in Chronic Myeloid Leukemia (CML)"

Advertisement
Quick Search
Advertisement
Advertisement

 

Searches Linking to this Trial