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The objective of this study is to measure and delineate the symptom burden experienced by patients with chronic myeloid leukemia (CML).
The Primary Aim is to develop and validate an M. D. Anderson Symptom Inventory (MDASI) module (the MDASI-CML), compliant with FDA standards for patient-reported outcomes (PROs), to measure the severity of multiple symptoms and the impact of these symptoms on daily functioning in patients with CML.
There are 3 parts to this study. In Part 1, patients will complete interviews and questionnaires about CML symptoms once. In Part 2, the importance of some symptoms to patients with CML will be rated by physicians, nurses, patients, and caregivers. In Part 3, patients will complete questionnaires about CML symptoms over 1 year.
Up to 218 participants will take part in this study. Up to 40 will be enrolled in Part 1 of this study. Up to 160 participants will be enrolled in Part 3 of this study. All will be enrolled at M. D. Anderson.
Observational Model: Case Control, Time Perspective: Prospective
Interview & Questionnaires, Rating Questionnaire, MDASI-CML Questionnaire
UT MD Anderson Cancer Center
M.D. Anderson Cancer Center
Published on BioPortfolio: 2014-07-23T21:11:10-0400
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