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Measurements of Colloid Osmotic Pressure in Interstitial Fluid and Plasma in Healthy and Sick Children

2014-08-27 03:16:48 | BioPortfolio

Summary

The purpose of this study is to measure colloid osmotic pressure in interstitial fluid and plasma in healthy children under two years, in asphyxiated babies and in children undergoing heart surgery.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Colloid Osmotic Pressure

Location

Haukeland University hospital
Bergen
Norway
5000

Status

Recruiting

Source

Haukeland University Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:48-0400

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Medical and Biotech [MESH] Definitions

RED BLOOD CELL sensitivity to change in OSMOTIC PRESSURE. When exposed to a hypotonic concentration of sodium in a solution, red cells take in more water, swell until the capacity of the cell membrane is exceeded, and burst.

The response of cells in sensing a difference in OSMOTIC PRESSURE between the inside and outside of the cell. This response includes signaling from osmotic sensors to activate transcription factors, which in turn regulate the expression of osmocompensatory genes, all functioning to maintain CELL VOLUME and the water concentration inside the cells.

The pressure required to prevent the passage of solvent through a semipermeable membrane that separates a pure solvent from a solution of the solvent and solute or that separates different concentrations of a solution. It is proportional to the osmolality of the solution.

A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules.

Solutions that have a lesser osmotic pressure than a reference solution such as blood, plasma, or interstitial fluid.

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