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Xylitol Syrup for the Prevention of Acute Otitis Media in Otitis-prone Children

2014-07-23 21:11:12 | BioPortfolio

Summary

The primary objective of the proposed study is to determine the effectiveness and safety of orally administered viscous-adherent xylitol syrup given in a dose of five grams three times daily for 12 weeks in reducing the incidence of clinically-diagnosed acute otitis media (ear infection) in children with a history of recurrent acute otitis media.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Conditions

Acute Otitis Media

Intervention

Xylitol syrup, Placebo

Location

Children's Hospital Boston
Boston
Massachusetts
United States
02115

Status

Recruiting

Source

Children's Hospital Boston

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:11:12-0400

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Medical and Biotech [MESH] Definitions

Inflammation of the ear, which may be marked by pain (EARACHE), fever, HEARING DISORDERS, and VERTIGO. Inflammation of the external ear is OTITIS EXTERNA; of the middle ear, OTITIS MEDIA; of the inner ear, LABYRINTHITIS.

Inflammation of the middle ear with purulent discharge.

Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.

Inflammation of the honeycomb-like MASTOID BONE in the skull just behind the ear. It is usually a complication of OTITIS MEDIA.

Inflammation of the middle ear with a clear pale yellow-colored transudate.

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