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Pharmacokinetics of MK4305 in Patients With Hepatic Insufficiency

2014-08-27 03:16:52 | BioPortfolio

Summary

This study will determine whether the plasma concentration-time profile and pharmacokinetics of MK4305 in patients with moderate and mild hepatic insufficiency are similar to those observed in healthy patients.

Description

Study Design:

If there is no significant difference in the pharmacokinetics of MK4305 between healthy subjects and moderate hepatic insufficiency patients in Part I of the study, then the study will not continue into Part II.

Anticipated Sample Size:

32 (16 in each Part: 8 healthy and 8 patients)

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Insomnia

Intervention

MK4305

Status

Completed

Source

Merck

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:52-0400

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Medical and Biotech [MESH] Definitions

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