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A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular Hemorrhage

2014-08-27 03:16:54 | BioPortfolio

Summary

The purpose of this study is to determine if usage of early lumbar drainage leads to improved outcome, less shunt surgery and less catheter associated complications in patients with communicating hydrocephalus after intracerebral hemorrhage with severe ventricular involvement.

Description

All patients requiring external ventricular drain (EVD) for treatment of acute obstructive hydrocephalus receive intraventricular fibrinolysis with rt-PA via the ventricular catheter. Lumbar drainage (LD) is inserted at a timepoint, when communication between the internal and the external CSF-spaces is recognizable on CT ("opening" of third and fourth ventricle and aqueduct).

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Intracerebral Hemorrhage

Intervention

Lumbar drainage

Location

Neurology Department, University of Erlangen-Nuremberg
Erlangen
Germany
91054

Status

Recruiting

Source

University of Erlangen-Nürnberg Medical School

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:54-0400

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Medical and Biotech [MESH] Definitions

Tapping of the subarachnoid space in the lumbar region, usually between the third and fourth lumbar vertebrae.

The lumbar and sacral plexuses taken together. The fibers of the lumbosacral plexus originate in the lumbar and upper sacral spinal cord (L1 to S3) and innervate the lower extremities.

A nerve originating in the lumbar spinal cord (usually L2 to L4) and traveling through the lumbar plexus to provide motor innervation to extensors of the thigh and sensory innervation to parts of the thigh, lower leg, and foot, and to the hip and knee joints.

Hemorrhage within the orbital cavity, posterior to the eyeball.

Intraocular hemorrhage from the vessels of various tissues of the eye.

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