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Nicardipine Versus Labetalol During Intubation

2014-07-24 14:10:28 | BioPortfolio

Summary

The aim of this study was to compare the efficacy of nicardipine and labetalol in attenuation of cardiovascular responses to endotracheal intubation.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Prevention

Conditions

Patients Who Are Intubated for General Anesthesia

Intervention

labetalol, nicardipine

Location

Seoul National University Bundang Hospital
Seongnam-si
Gyeonggi-do
Korea, Republic of
463-707

Status

Recruiting

Source

Seoul National University Bundang Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:10:28-0400

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Medical and Biotech [MESH] Definitions

Abnormally slow pace of regaining CONSCIOUSNESS after general anesthesia (ANESTHESIA, GENERAL) usually given during surgical procedures. This condition is characterized by persistent somnolence.

Procedure in which patients are induced into an unconscious state through use of various medications so that they do not feel pain during surgery.

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not produce any excitation but has poor analgesic and muscle relaxant properties. Small doses have been shown to be anti-analgesic and lower the pain threshold. (From Martindale, The Extra Pharmacopoeia, 30th ed, p920)

The period of emergence from general anesthesia, where different elements of consciousness return at different rates.

A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state. (From Martindale, The Extra Pharmacopoeia, 30th ed, p919)

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