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A Multiple Dose Study of TD-1211 in Healthy Volunteers and Patients With Opioid-Induced Constipation

2014-08-27 03:16:59 | BioPortfolio

Summary

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of TD-1211 in healthy subjects and activity in subjects with opioid-induced constipation (OIC).

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Healthy

Intervention

TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, Placebo

Location

Clinical Research Unit
San Antonio
Texas
United States
78209

Status

Recruiting

Source

Theravance

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:16:59-0400

Clinical Trials [2 Associated Clinical Trials listed on BioPortfolio]

TD-1211 Single-Dose Study in Elderly and Young Healthy Subjects

The purpose of this study is to measure the way in which TD-1211 is absorbed and eliminated by the body and to evaluate whether it is safe and well tolerated.

A Study to Evaluate Efficacy and Safety of Methacholine Chloride Challenge Test in Diagnosis of Adult Asthma

The purpose of this study is to evaluate efficacy and safety of Methacholine Chloride challenge test in diagnosis of adult asthma

PubMed Articles [3 Associated PubMed Articles listed on BioPortfolio]

Referral patterns and patient characteristics at the first visit to a scoliosis center: a 2-year experience in South Korea without a school scoliosis-screening program.

OBJECTIVE The need for scoliosis screening remains controversial. Nationwide school screening for scoliosis has not been performed in South Korea, and there are few studies on the referral patterns of...

Full structure and insight into the gene cluster of the O-specific polysaccharide of Yersinia intermedia H9-36/83 (O:17).

Lipopolysaccharide was isolated from bacteria Yersinia intermedia H9-36/83 (O:17) and degraded with mild acid to give an O-specific polysaccharide, which was isolated by GPC on Sephadex G-50 and studi...

Balanced Crystalloids versus Saline in Critically Ill Adults.

Background Both balanced crystalloids and saline are used for intravenous fluid administration in critically ill adults, but it is not known which results in better clinical outcomes. Methods In a pra...

Medical and Biotech [MESH] Definitions

None available.

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