A Multiple Dose Study of TD-1211 in Healthy Volunteers and Patients With Opioid-Induced Constipation

2014-08-27 03:16:59 | BioPortfolio


The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of TD-1211 in healthy subjects and activity in subjects with opioid-induced constipation (OIC).

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment




TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, TD-1211, Placebo


Clinical Research Unit
San Antonio
United States





Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:16:59-0400

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PubMed Articles [3 Associated PubMed Articles listed on BioPortfolio]

Referral patterns and patient characteristics at the first visit to a scoliosis center: a 2-year experience in South Korea without a school scoliosis-screening program.

OBJECTIVE The need for scoliosis screening remains controversial. Nationwide school screening for scoliosis has not been performed in South Korea, and there are few studies on the referral patterns of...

Full structure and insight into the gene cluster of the O-specific polysaccharide of Yersinia intermedia H9-36/83 (O:17).

Lipopolysaccharide was isolated from bacteria Yersinia intermedia H9-36/83 (O:17) and degraded with mild acid to give an O-specific polysaccharide, which was isolated by GPC on Sephadex G-50 and studi...

Balanced Crystalloids versus Saline in Critically Ill Adults.

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Medical and Biotech [MESH] Definitions

None available.

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