Gut Oxygenation and Laparoscopy

2014-08-27 03:17:00 | BioPortfolio


Patients with left-colon cancer will be randomized to laparoscopic or laparotomic operation. during surgery and for 6 days after operation, intestinal oxygen tension and ischemia-reperfusion injury markers will be evaluated to understand if pneumoperitoneum is associated with reduced splanchnic blood flow and ischemia-reperfusion injury.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment




Laparoscopy, left colectomy by laparotomy


San Gerardo Hospital




University of Milano Bicocca

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:17:00-0400

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Medical and Biotech [MESH] Definitions

A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.

Placement of one of the surgeon's gloved hands into the ABDOMINAL CAVITY to perform manual manipulations that facilitate the laparoscopic procedures.

Incision into the side of the abdomen between the ribs and pelvis.

Diversion of the flow of blood from the pulmonary veins directly to the aorta, avoiding the left atrium and the left ventricle (Dorland, 27th ed). This is a temporary procedure usually performed to assist other surgical procedures.

Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)

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Colorectal Cancer
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