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The purpose of this study is to look at red blood cell(RBC)transfusions in trauma patients and evaluate for any differences between the age of the RBCs and how they were stored. The investigators will specifically look for the following differences between study groups:
1. the transfused red blood cells' ability to delivery oxygen to the tissues
2. changes in the how the RBCs' look or act under a microscope and
3. how the subject's internal organs are working and if they develop any infections
Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Prevention
Red Blood Cells
Oregon Health & Science University
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Oregon Health and Science University
Published on BioPortfolio: 2014-08-27T03:17:05-0400
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The area of hematology that is concerned with the transfusion of blood and blood components, and in prevention and treatment of adverse effects from BLOOD TRANSFUSION errors.
Complications of BLOOD TRANSFUSION.
In utero transfusion of BLOOD into the FETUS for the treatment of FETAL DISEASES, such as fetal erythroblastosis (ERYTHROBLASTOSIS, FETAL).
The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)
Reinfusion of blood or blood products derived from the patient's own circulation. (Dorland, 27th ed)
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