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This is a multicenter, single-dose trial to evaluate the efficacy of a novel ibuprofen formulation compared to a placebo in patients with a fever due to a flu-like upper respiratory illness. Patients will be randomized to receive either a single dose of a novel ibuprofen formulation (equal to 400mg ibuprofen) or a single dose of a placebo. After taking the study drug, patients will measure their temperature at pre-specified time points over an 8 hour period.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Published on BioPortfolio: 2014-08-27T03:17:11-0400
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Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.
An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.
An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.
An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.
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