Chronic Alcohol and Brain Stress Circuit Response
Summary
Alcoholism is among the top three causes of preventable death and disease in the US (Mokdad et al., 2004; Room et al., 2005). Stress plays an important role in the development of alcoholism and in high vulnerability to alcohol relapse. This study will provide a greater understanding of the mechanism by which stress and alcohol consumption interacts to influence development of compulsive alcohol seeking and vulnerability to stress-induced drinking, and the results will have significant implications for the development of new prevention and treatment interventions for alcoholism.
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Conditions
Stress
Location
Yale Stress Center
New Haven
Connecticut
United States
06519
Status
Recruiting
Source
Yale University
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT01031264
- Information obtained from ClinicalTrials.gov on July 15, 2010
Published on BioPortfolio: 2014-07-23T21:11:24-0400
Clinical Trials
Impact of Thermal Stress on Pulmonary Absorption and Toxicokinetics of 3 Organic Solvents
In Quebec, thousands of workers are concomitantly exposed to heat and chemical compounds. Exposure to heat induces physiological responses that help maintaining a stable body temperature. ...
Study of the Ability of Clarithromycin to Induce Oxidative Stress
The purpose of the study is to examine whether Klacid® (Clarithromycin) will induce oxidative stress (stress from oxygen) in healthy subjects. This is done by measuring the content of a p...
Curb, Alter, Lower, or Manage Stress in HIV: CALMS-HIV
The purpose of this study is to determine the effectiveness of a stress management group intervention for people with HIV. The study will evaluate several outcomes, including perceived str...
Stress Management for High Blood Pressure
The purpose of this research study is to examine the efficacy of two stress management interventions in reducing blood pressure (BP) in patients who have prehypertension (BP between 120/80...
Evaluation of Aromatherapy on Academic Stress
Stress affects the health and is prevalent among medicine and pharmacy students. A number of factors such as busy schedules, course load and lack of recreational time during semesters as w...
PubMed Articles
Stress affects us in every environment and it is also present in the educational sphere. Previous studies have reported a high prevalence of stress in university students. The Student Stress Inventory...
New perspectives in stress research: 2016 neurobiology of stress workshop.
Stress: Common themes toward the next frontier.
"Stress is complicated". A phrase uttered by many a stress researcher. This is true, from the vast array of stimuli considered "stressors" to the interactive and hormetic nature of the molecular, cell...
Familial risk for insomnia is associated with abnormal cortisol response to stress.
Abnormalities in the stress system have been implicated in insomnia. However, studies examining physiological stress regulation in insomnia have not consistently detected differences in the hypothalam...
Type 1 diabetes (T1D) is a chronic source of metabolic and neuropsychological stress, which may eventually lead to autonomic neuropathy and other complications related to micro- and macro-vasculopathi...
Medical and Biotech [MESH] Definitions
Stress Disorders, Traumatic, Acute
A class of traumatic stress disorders that is characterized by the significant dissociative states seen immediately after overwhelming trauma. By definition it cannot last longer than 1 month, if it persists, a diagnosis of post-traumatic stress disorder (STRESS DISORDERS, POST-TRAUMATIC) is more appropriate.
Oxidative Stress
A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).
Stress, Psychological
Stress wherein emotional factors predominate.
Relaxation Therapy
Treatment to improve one's health condition by using techniques that can reduce PHYSIOLOGICAL STRESS; PSYCHOLOGICAL STRESS; or both.
Stress Disorders, Post-traumatic
A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event.
