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Observational Study on Anti-Tat Immune Response in HIV-1-infected Asymptomatic Adult Subjects

2014-08-27 03:17:24 | BioPortfolio

Summary

The present study is designed as a prospective observational study directed at evaluating the frequency, magnitude, quality and persistence (primary endpoint) of the anti-Tat immune response in HIV-1 infected asymptomatic individuals, and to prospectively evaluate the immunological, virological and clinical outcome of anti-Tat positive versus anti-Tat negative drug naїve subjects (secondary endpoint) in order to determine the impact of anti-Tat immunity on HIV disease progression as well as the potential use of anti-Tat immune response assessment for the clinical and therapeutic management of infected patients. This survey, that will evaluate a large number of subjects, will provide important information for the design, planning and conduction of future therapeutic vaccine trials based on the HIV-1 Tat protein in asymptomatic subjects.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

HIV Infections

Location

S.M. Goretti Hospital
Latina
Rome
Italy
41100

Status

Recruiting

Source

Istituto Superiore di Sanita

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:17:24-0400

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