PCV10 Reactogenicity and Immunogenicity Study - Malindi

2014-08-27 03:17:25 | BioPortfolio


The World Health Organization has recommended that developing countries should incorporate pneumococcal conjugate vaccine (PCV) into their routine immunization schedules. The Kenya Ministry of Health anticipates introducing a new formulation of PCV, PCV10, into the routine childhood immunization schedule in 2010. In the areas of Kenya that have been designated to monitor the impact of vaccine, a catch-up campaign will be implemented to vaccinate children aged 12-59 months. PCV10 has been found to be safe and effective in infants. It is licensed for use in children up to 2 years of age, but its use as a primary series in children over age 12 months has not been evaluated. This study will assess the immunogenicity and reactogenicity of PCV10 first administered at an age of 12-59 months.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Prevention


Pneumococcal Pneumonia


PCV10 and DTaP, PCV10 and DTaP, hepatitis A vaccine, DTaP, PCV10


Malindi District Hospital




KEMRI-Wellcome Trust Collaborative Research Program

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:17:25-0400

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Medical and Biotech [MESH] Definitions

Any vaccine raised against any virus or viral derivative that causes hepatitis.

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