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Safety and Immunogenicity of MVA.HIVconsv in HIV-1 Seropositive Adults on HAART

2014-08-27 03:17:33 | BioPortfolio

Summary

In this study, the novel vaccine candidate, MVA.HIVconsv, will be tested for safety, tolerability and immunogenicity in HIV-1-seropositive subjects receiving effective antiretroviral therapy.

MVA.HIVconsv will be tested as a single vaccine modality, as a prelude to testing in a heterologous viral vector boost regimen which will include a replication-defective simian adenovirus expressing the same immunogen.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

HIV-1

Intervention

MVA.HIVconsv low dose, Placebo low dose, MVA.HIVconsv high dose, Placebo high dose

Location

Weatherall Institute of Molecular Medicine
Oxford
Oxons
United Kingdom
OX3 9DS

Status

Recruiting

Source

University of Oxford

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:17:33-0400

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