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Clinical Trial of Donepezil Between the Patients With Alzheimer's Disease and Mixed Dementia

2014-08-27 03:17:37 | BioPortfolio

Summary

To compare the clinical efficacy of donepezil between patients with Alzheimer's disease and Mixed Dementia.

Description

The purposes of this study are:

1. to compare the clinical efficacy of donepezil between patients with Alzheimer's disease and Mixed Dementia

2. to help to clinicians in choosing the best treatment for patients with mixed dementia

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Alzheimer's Disease

Intervention

donepezil

Location

Samsung Medical Center
Seoul
#50 Ilwon-Dong, Kangnam-Gu
Korea, Republic of
135-710

Status

Recruiting

Source

Samsung Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:17:37-0400

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PubMed Articles [14853 Associated PubMed Articles listed on BioPortfolio]

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[This corrects the article on p. 698 in vol. 14.].

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Medical and Biotech [MESH] Definitions

Abnormal structures located chiefly in distal dendrites and, along with NEUROFIBRILLARY TANGLES and SENILE PLAQUES, constitute the three morphological hallmarks of ALZHEIMER DISEASE. Neuropil threads are made up of straight and paired helical filaments which consist of abnormally phosphorylated microtubule-associated tau proteins. It has been suggested that the threads have a major role in the cognitive impairment seen in Alzheimer disease.

Vaccines or candidate vaccines used to prevent or treat ALZHEIMER DISEASE.

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