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CNI-free "Bottom"-up Immunosuppression in Patients Undergoing Liver Transplantation With MELD-scores>25 and/or an eGFR (Abbreviated MDRD-Formula) ≤50 mL/Min

2014-08-27 03:17:37 | BioPortfolio

Summary

The primary objective of the trial is to evaluate efficacy and safety of delayed introduction (up to 30 days post-transplantation in patients without signs of acute rejection that had received an aIL-2 induction and MMF) of either cyclosporine or everolimus versus a 5-day delay of cyclosporine in combination with MMF.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Renal Impairment

Intervention

delayed, low-dose CNI, BU-CNI, BU-Everolimus

Location

Regensburg University Hospital
Regensburg
Bavaria
Germany
93053

Status

Not yet recruiting

Source

University of Regensburg

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:17:37-0400

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