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To evaluate the efficiency of a microdevice for circulating tumor cells isolation and to correlate the circulating titre with response and progression.
- Validate the clinical use of a mircofluidic device to capture circulating timor cells from a broad range of tumor types
- Characterize and identify these circulating tumor cells and demostrate cell viability with this capture method
- Apply this technology in clinically relevant settings and correlate to response to treatment and disease progression
- Elucidate predictive and pharmacodynamic biomarkers in the context of early phase trials of novel therapeutics
Observational Model: Cohort, Time Perspective: Prospective
National Cancer Centre
National Cancer Centre, Singapore
Published on BioPortfolio: 2014-08-27T03:17:38-0400
The goal of this clinical research study is to learn if ponatinib can help to control CML in chronic phase. The safety of this drug will also be studied. Ponatinib is designed to block t...
A Kidney Transplant Study to Look at the Effects of Taking Fixed Doses of CellCept Versus Taking Doses of CellCept Based on the Concentration of CellCept in the Blood When Taking Full or Reduced Dose Calcineurin Inhibitors
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Comparison of olaparib against a placebo in patients with ovarian cancer whose cancer has already improved by taking platinum based chemotherapy. The patients must also have a fault in the...
Blood grouping is conventionally done with invasive method by taking blood samples. The objective of this study is to determine blood group with uninvasive procedure by taking fingerprints of the part...
Corrigendum: Mueller EL, Sabbatini A, Gebremariam A, et al. Why pediatric patients with cancer visit the emergency department: United States, 2006-2010. Pediatr Blood Cancer. 2015;62:490-495. DOI: 10.1002/pbc.25288.
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Corrigendum: Ermoian RP, Breneman J, Walterhouse DO, et al. 45 Gy is not sufficient radiotherapy dose for Group III orbital embryonal rhabdomyosarcoma after less than complete response to 12 weeks of ARST0331 chemotherapy. Pediatr Blood Cancer. 2017;64:E26540. https://doi.org/10.1002/pbc.26540.
The phenotypic heterogeneity of circulating tumor cells (CTC) in peripheral blood and disseminated tumor cells (DTC) in bone marrow is an important constraint for clinical decision making. Here, we in...
The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.
Skills and strategies, unrelated to the traits a test is intended to measure, that may increase test takers' scores -- may include the effects of coaching or experience in taking tests. (ERIC Thesaurus)
A cancer registry mandated under the National Cancer Act of 1971 to operate and maintain a population-based cancer reporting system, reporting periodically estimates of cancer incidence and mortality in the United States. The Surveillance, Epidemiology, and End Results (SEER) Program is a continuing project of the National Cancer Institute of the National Institutes of Health. Among its goals, in addition to assembling and reporting cancer statistics, are the monitoring of annual cancer incident trends and the promoting of studies designed to identify factors amenable to cancer control interventions. (From National Cancer Institute, NIH Publication No. 91-3074, October 1990)
A deoxycytidine derivative and fluorouracil PRODRUG that is used as an ANTINEOPLASTIC ANTIMETABOLITE in the treatment of COLON CANCER; BREAST CANCER and GASTRIC CANCER.
Unlawful act of taking property.
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