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Influence of the Proton Pump Inhibitor Omeprazole on the Anti-Platelet of P2Y12 Antagonists in Subjects With Coronary and Peripheral Artery Disease

2014-08-27 03:17:48 | BioPortfolio

Summary

To determine if prasugrel is superior to clopidogrel in providing adequate antiplatelet effect in a high risk population that requires concomitant use of a Proton Pump Inhibitor (PPI).

Description

To evaluate if simultaneous treatment with the PPI omeprazole and a P2Y12 receptor antagonist will influence the effect of either clopidogrel and/or prasugrel on platelet reactivity in patients with Coronary Artery Disease (CAD) or Peripheral Arterial Disease (PAD).

Study Design

Observational Model: Case-Crossover, Time Perspective: Prospective

Conditions

Coronary or Peripheral Artery Disease

Location

University of Oklahoma Health Sciences Center
Oklahoma City
Oklahoma
United States
73190

Status

Not yet recruiting

Source

University of Oklahoma

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:17:48-0400

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